Glucagon-like peptide-1, satiety and appetite control
نویسندگان
چکیده
منابع مشابه
Glucagon-like peptide-1, satiety and appetite control.
After eating a meal several subjective and behavioural changes occur. Normally hunger is reduced, the feeling of fullness increases and eating is inhibited. This state is called post-ingestive satiety: the inhibition of appetite resulting from food consumption. What mechanisms control this phenomenon? During and after eating there occurs a series of overlapping physiological responses, most of ...
متن کاملGastrointestinal satiety signals III. Glucagon-like peptide 1, oxyntomodulin, peptide YY, and pancreatic polypeptide.
Many peptides are synthesized and released from the gastrointestinal tract and pancreas, including pancreatic polypeptide (PP) and the products of the gastrointestinal L cells, glucagon-like peptide 1 (GLP-1), oxyntomodulin, and peptide YY (PYY). Whereas their roles in regulation of gastrointestinal function have been known for some time, it is now evident that they also influence eating behavi...
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Ma Glucagon-like peptide-1-(7-36) amide (GLP-1) is a human incretin hormone responsible for the release of insulin in response to food. Pre-clinical and human physiological studies have demonstrated cardioprotection from ischemia-reperfusion injury. It can reduce infarct size, ischemic left ventricular dysfunction, and myocardial stunning. GLP-1 receptor agonists have also been shown to reduce ...
متن کاملGlucagon-like peptide 1 promotes satiety and suppresses energy intake in humans.
We examined the effect of intravenously infused glucagon-like peptide 1 (GLP-1) on subjective appetite sensations after an energy-fixed breakfast, and on spontaneous energy intake at an ad libitum lunch. 20 young, healthy, normal-weight men participated in a placebo-controlled, randomized, blinded, crossover study. Infusion (GLP-1, 50 pmol/ kg.h or saline) was started simultaneously with initia...
متن کاملDIGESTIVO Interactions between gastric emptying and satiety, withspecial reference to glucagon-like peptide-1
The slowing of gastric emptying is an important mechanism for the satiating effect of gut peptide signaling. After food intake, cholecystokinin (CCK), as well as glucagon-like peptide-1 (GLP-1) and glucagon-like peptide-2 (GLP-2), are released from the gastrointestinal tract to mediate satiety. In humans, CCK and the GLP-1 have been found to cause satiety in both normal and obese subjects. This...
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ژورنال
عنوان ژورنال: British Journal of Nutrition
سال: 1999
ISSN: 0007-1145,1475-2662
DOI: 10.1017/s0007114599000483